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This dissertation was written as part of the MSc in Banking and Finance at the Interna-tional Hellenic University. Using financial data before and after the recent crisis, I have conducted a unique panel dataset of approximately 33 banks from Greece, Ireland, Italy, Portugal and Spain. With the intention of evaluating and assessing the impact of securitisation on the fi-nancial performance of these banks, I analyse the regression output of a securitisation index, number of deals per year, on ratios that denote bank profitability, liquidity and financial stability in the fields of risk and efficiency. On average my results indicate that only profitability and capital adequacy are affected by the presence of securitisa-tion. Return on average assets (ROAA) is found positive affected by securitisation deals, while Tier I is proved to have a negative relationship. Although, the sample size is small and the explanatory power is limited, the regression results confirm previous empirical findings of the related literature and so partially does the comparative anal-ysis of these two ratios among the examined countries. I would like to thank my supervisor, Prof. Theothoros Syriopoulos, for his constant sup-port and encouraging and valuable comments during my work on this dissertation. I also thank my family and my partner, Christos Vathilakis, who patiently stood by me in every difficult and pleasant moment of this wonderful journey.