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dc.contributor.author
Liapi, Eleni
en
dc.date.accessioned
2023-04-20T09:41:49Z
dc.date.available
2023-04-20T09:41:49Z
dc.date.issued
2023-04-20
dc.identifier.uri
https://repository.ihu.edu.gr//xmlui/handle/11544/30148
dc.rights
Default License
dc.subject
Nucleotide
el
dc.subject
Non-coding
el
dc.subject
Sequence(s)
el
dc.subject
Cardiovascular
el
dc.title
Description of cardiovascular papers containing errors in non-coding RNA research
en
heal.type
masterThesis
en_US
heal.dateAvailable
2022-09-09
heal.language
en
en_US
heal.access
free
en_US
heal.license
http://creativecommons.org/licenses/by-nc/4.0
en_US
heal.recordProvider
School of Economics, Business Administration & Legal Studies, MSc in Bioeconomy: Biotechnology and Law
en_US
heal.publicationDate
2022-09-09
heal.bibliographicCitation
Eleni Liapi, Description of cardiovascular papers containing errors in non-coding RNA research, School of Economics, Business Administration and Legal Studies, International Hellenic University, MSc in Bioeconomy: Biotechnology and Law, 2022
en
heal.abstract
This dissertation was written as part of the MSc in Bioeconomy: Biotechnology and Law at the International Hellenic University. Publishing scientific results in biomedical journals is a common way of disseminating research findings. In the field of molecular cardiology, studies often report gene expression results using samples of human (patients) and/or animal origin. For reasons of transparency, reproducibility, and accordance to relevant, issued guidelines, gene expression studies require that scientists report which set of tools and reagents they used to detect and quantify genes, including the family of non-coding RNAs. However, recent concerns over inauthentic articles, coming from illegitimate publishing schemes, termed as “paper mills” have alarmed scientists to carefully examine gene-expression claims in articles studying molecular processes involving non-coding RNAs. This Thesis aimed to investigate the extent of erroneous nucleotide sequences in scientific papers involving non-coding RNA gene expression in cardiovascular research. We addressed the relative frequency of nucleotide errors and non-disclosures of nucleotide sequences, the roles of publication speed, number of authors, potential accumulation in specific Journals and regional specificity of their occurrence. Results suggest that worries over ‘paper mills’ in biomedical research also apply to cardiovascular research on non-coding RNAs. We finally discuss our findings and study limitations in relation to earlier publication guidelines for nucleotide-based reagents and the thoroughness of the peer-review process to identify this type of errors in cardiovascular research.
en
heal.advisorName
Dr. Halffman, Willem
el
heal.committeeMemberName
Dr. Genitsaris, Savvas
en
heal.committeeMemberName
Prof. Dr. de Regt, Henk W.
el
heal.academicPublisher
IHU
en
heal.academicPublisherID
ihu
en_US


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